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Exposure-epidemiology
DENAMIC investigate differences in prenatal and neonatal exposure to a selected number of suspected neurotoxic environmental pollutants in four different European regions. Data and samples from existing European cohorts with different exposure profiles from Norway, Netherlands, Slovakia and Spain will be made available for DENAMIC. These studies will also be used to study possible associations between the selected environmental pollutants with neurodevelopmental outcome, in particular cognitive development (e.g. ADHD).
In addition, a new tailor-made cohort of mother-child pairs is set up. In this specific cohort, associations between chemical exposure and learning (cognitive) and neurobehavioural (ADHD, ASD, anxiety) development or disorders will be studied. The tailor-made cohort will also be used to test the validity and usability of the integrated screening tools and methods for neurotoxicity developed in the hazard characterization. This study will be used to explore the relevance of selected biomarkers.
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